Lotioned wipe product to reduce adhesion of soils or exudates to the skin

ABSTRACT

An anti-stick agent that may be incorporated into an aqueous medium to assist in the prevention of soils and bodily exudates adhering to the skin. A substrate may be utilized to assist in delivering the anti-stick agent to the skin.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application is a continuation of U.S. application Ser. No.11/807,288, filed on May 25, 2007 now U.S. Pat. No. 8,221,774, which isincorporated by reference in its entirety, which claims the benefit ofU.S. Provisional Application Nos. 60/812,828, filed on Jun. 12, 2006,and 60/855,426, filed on Oct. 31, 2006, which are incorporated herein byreference in their entirety.

FIELD OF THE INVENTION

A lotioned wipe product comprising a substrate and a lotion in contactwith the substrate, the lotion comprising an anti-stick agent may beused for delivering an improved body cleansing performance. The lotionmay help reduce adhesion of soils or exudates to the skin.

BACKGROUND OF THE INVENTION

Cleaning the skin is a personal hygiene problem not always easilysolved. Dry tissue products are the most commonly used cleansingproducts post-defecation, post-urination and during menstruation. Drytissue products are also commonly used to remove soils, such as food anddirt, from the skin. Dry tissue products, such as those commonly used,are generally referred to as “toilet paper,” “toilet tissue,” or “papertowels.” In addition to the use of dry tissue products, it is becomingincreasingly frequent to use moistened substrates, such as wet wipes,for the purpose of cleansing the face and body after soiling, and theanus, the genital area, the perinea, and the peri-anal area after thevoiding of bodily exudates. So called “wet wipes” are generally afibrous structure impregnated with a water or oil-based lotion.

For the purpose of the present document, the anus, the perinea, theperineal area and the vulvar area are all terms indicating the body areaof the pelvis between, around and including the anus and the externalgenitalia.

Both the perineal area and the vulvar area are marked by the presence offine folds/wrinkles (sulci) and hair follicles, both of which make theseregions more difficult anatomical areas to cleanse. During defecation,fecal matter is excreted through the anus and tends to accumulate inhard to reach locations such as around the base of hairs and in thesulci of the skin's surface. During menstruation, menses may accumulateon the skin and hair after the use of a sanitary napkin. As the fecal ormenstrual matter dehydrates upon exposure to air or upon contact with anabsorbent implement such as tissue paper, diaper, or sanitary napkin, itadheres more tenaciously to the skin and hair. Subsequent removal of theremaining dehydrated exudates may be even more difficult and may resultin inadequate cleansing. Among those negatives associated with thefailure of adequate cleansing are irritation, redness, desquamation,infections, unpleasant odor, or other kinds of personal discomfort orhealth related issues.

People suffering from pathological conditions (such as hemorrhoids,fissures, cryptitis, etc.) are even more susceptible to the negativeslisted above. Common hygienic concerns make the benefits of a goodcleansing after defecation, menstruation, and urination very relevant tobabies, toddlers, children and adults. Cleansing must be efficient interms of removal of residues and gentle in terms of absence ofirritation caused by the cleansing. Wet-wipes bring a response to thatbasic need.

In comparison to dry tissue products, wet wipes have several benefitsincluding:

-   -   The enabling of a better lubrication during the use of the wipe,        thereby reducing the abrasiveness of the cleansing operation;    -   The hydration of the residues, thus enhancing their removal from        the skin or hair;    -   The hydration of the skin tissue; and    -   The ability to deliver a soothing or protective lotion to the        skin that can remain on the skin after the cleansing operation.

Manufacturers of wet wipes have tried to develop wipes products thatdeliver the right balance between normally antagonistic concepts suchas:

-   -   Enhancing the removal of soil while protecting the skin from        irritation and abrasion.    -   The long lasting feeling of comfortable cleanliness while        avoiding a greasy feeling on the skin.

There still remains a need not only for a wet wipe that cleanseffectively but that also simultaneously reduces or prevents theadhesion of soils or exudates to the skin. Such a wipe would greatlyfacilitate cleansing. The facilitation of cleansing by such a wipe maybe reflected by a reduced deposition of soils or exudates on the skinfrom subsequent insults. As a result, there may be a reduction in theamount of soils or exudates on the skin at the time of the nextcleaning, easier removal of the soils or exudates from the skinresulting in less abrasive damage, reduced smearing of the soils orexudates on the skin, and/or improved capture/retention of the soils orexudates on a substrate, such as a wet wipe, or within an absorbentarticle. The net result may be that the time and effort required by theindividual to achieve a satisfactory state of cleanliness may beminimized.

There exists a further need for a wet wipe that substantially reduces orprevents adhesion of soils or exudates to the skin in a manner that istransparent to the individual using the wipe, i.e. does not require achange in habit such as the use of a separate wipe or leave anundesirable greasy layer on the skin surface.

SUMMARY OF THE INVENTION

A lotioned wipe product comprising a substrate and a lotion in contactwith the substrate, the lotion comprising an anti-stick agent whereinthe lotion may be effective at leaving less than about 10% w/w residualsoils or exudates as measured by the Anti-Stick Screening Method. Theanti-stick agent may be present at a concentration of equal to or lessthan about 50% w/w of the lotion composition. The anti-stick agent maybe water soluble.

The anti-stick agent may be selected from the group consisting ofnon-polymeric anti-stick agents, polymeric anti-stick agents, siliconecopolyols, mono-functional heteroatom oxide ethers, poly-functionalheteroatom oxide esters, and combinations thereof.

The lotion may further comprise an emollient and a surfactant.

An article of commerce may comprise a container housing a lotioned wipeproduct.

A method of preventing the adherence of soils or exudates to the skinmay comprise a step of contacting the lotioned wipe product to the skin.

BRIEF DESCRIPTION OF THE FIGURES

FIG. 1 is an example of the general structure to which siliconecopolyols may conform.

FIG. 2 is an example of the general structure to which a combination ofpolyoxyethylene, polyoxypropylene, and polyglycerol may conform.

FIG. 3 is an example of the general structure to which a mono-functionalheteroatom oxide ethoxylated ether may conform.

FIG. 4 is an example of the general structure to which a mono-functionalphosphonate ethoxylated ether may conform.

FIG. 5 is an example of the general structure to which a mono-functionalcarbonato ethoxylated ether may conform.

FIG. 6 is an example of the general structure to which a mono-functionalsulphonato ethoxylated ether may conform.

FIG. 7 is an example of the general structure to which a poly-functionalheteroatom oxide ester may conform.

FIG. 8 is an example of the general structure to which a poly-functionalphosphate ester may conform.

FIG. 9 is an example of the general structure to which a poly-functionalsulfate ester may conform.

FIG. 10 is an example of the general structure to which apoly-functional sulphonato ester may conform.

FIG. 11 is an example of the percent of artificial bowel movementresidual left on a forearm following anti-stick treatment asdemonstrated by the Anti-Stick Screening Method.

DETAILED DESCRIPTION OF THE INVENTION

The ease with which soils and bodily exudates are removed from the skinmay be related to the strength of the adhesive interactions between thesoils or exudates and the skin surface. A reduction in the adhesion ofthe soils or exudates to the skin may enable an easier removal of thesoils or exudates. A variety of materials (hereinafter referred to asanti-stick agents) have been identified that may reduce the strength ofadhesion of soils or exudates to the skin. A substrate in contact with alotion comprising an anti-stick agent may reduce the strength ofadhesion of soils or exudates to the skin. Such a combination of asubstrate and lotion may be a lotioned wipe product.

As defined herein, “weight/weight” or “w/w” refers to the weight of thecomponent being referenced versus the weight of the total material inreference. Therefore, the use of “w/w” in substrates refers to theweight of the individual substrate component versus the weight of thetotal substrate. The use of “w/w” in lotions refers to the weight of theindividual lotion component versus the total weight of the lotion. Theuse of “w/w” in water solubility refers to the weight of the materialversus the weight of the total water into which the material isdissolved. The use of “w/w” for residual artificial bowel movement (ABM)refers to the weight of the remaining artificial bowel movement on theskin versus the total weight of the artificial bowel movement applied tothe skin.

Substrate

A lotion may be in contact or associated with a substrate for use in thecleaning and removal of soils or exudates. “Substrate” is the generalterm to describe a piece of material, generally non-woven material, usedin cleansing body parts. In particular, many currently availablesubstrates may be intended for the cleansing of the perianal area afterdefecation. Other substrates may be available for the cleansing of theface or other body parts.

The substrate may be a nonwoven material. “Nonwoven” refers herein to afibrous structure made from an assembly of continuous fibers, coextrudedfibers, non-continuous fibers and combinations thereof, without weavingor knitting, by processes such as spunbonding, carding, meltblowing,airlaying, wetlaying, coform, or other such processes known in the artfor such purposes. The nonwoven structure may comprise one or morelayers of such fibrous assemblies, wherein each layer may includecontinuous fibers, coextruded fibers, noncontinuous fibers andcombinations thereof.

The fibers of the substrate may be any natural, cellulosic, and/orwholly synthetic material. Examples of natural fibers may includecellulosic natural fibers, such as fibers from hardwood sources,softwood sources, or other non-wood plants. The natural fibers maycomprise cellulose, starch and combinations thereof. Non-limitingexamples of suitable cellulosic natural fibers include, but are notlimited to, wood pulp, typical northern softwood Kraft, typical southernsoftwood Kraft, typical CTMP, typical deinked, corn pulp, acacia,eucalyptus, aspen, reed pulp, birch, maple, radiata pine andcombinations thereof. Other sources of natural fibers from plantsinclude, but are not limited to, albardine, esparto, wheat, rice, corn,sugar cane, papyrus, jute, reed, sabia, raphia, bamboo, sidal, kenaf,abaca, sunn, rayon (also known as viscose), lyocell, cotton, hemp, flax,ramie and combinations thereof. Yet other natural fibers may includefibers from other natural non-plant sources, such as, down, feathers,silk, cotton and combinations thereof. The natural fibers may be treatedor otherwise modified mechanically or chemically to provide desiredcharacteristics or may be in a form that is generally similar to theform in which they can be found in nature. Mechanical and/or chemicalmanipulation of natural fibers does not exclude them from what areconsidered natural fibers with respect to the development describedherein.

The synthetic fibers can be any material, such as, but not limited to,those selected from the group consisting of polyesters (e.g.,polyethylene terephthalate), polyolefins, polypropylenes, polyethylenes,polyethers, polyamides, polyesteramides, polyvinylalcohols,polyhydroxyalkanoates, polysaccharides, and combinations thereof.Further, the synthetic fibers can be a single component (i.e., singlesynthetic material or mixture makes up entire fiber), bi-component(i.e., the fiber is divided into regions, the regions including two ormore different synthetic materials or mixtures thereof and may includeco-extruded fibers and core and sheath fibers) and combinations thereof.It is also possible to use bicomponent fibers. These bicomponent fiberscan be used as a component fiber of the structure, and/or they may bepresent to act as a binder for the other fibers present in the fibrousstructure. Any or all of the synthetic fibers may be treated before,during, or after manufacture to change any desired properties of thefibers.

In certain embodiments, it may be desirable to have particularcombinations of fibers to provide desired characteristics. For example,it may be desirable to have fibers of certain lengths, widths,coarseness or other characteristics combined in certain layers orseparate from each other. The fibers may be of virtually any size andmay have an average length from about 1 mm to about 60 mm. Average fiberlength refers to the length of the individual fibers if straightenedout. The fibers may have an average fiber width of greater than about 5micrometers. The fibers may have an average fiber width of from about 5micrometers to about 50 micrometers. The fibers may have a coarseness ofgreater than about 5 mg/100 m. The fibers may have a coarseness of fromabout 5 mg/100 m to about 75 mg/100 m.

Additionally, it may be desirable for the fibers to have certaincompositional characteristics. For example, in the instance where thelotion may comprise hydrophilic (i.e. water soluble) ingredients thatultimately are intended to be imparted to the skin during cleansing, itmay be desirable that the fibers comprise hydrophobic materials toreduce the tendency of the hydrophilic ingredients to adhere to thefibers, thereby reducing their availability to the skin. Without beingbound by theory, it is believed that the lotion ingredients maypartition between the lotion and the fibers during storage, and betweenthe lotion and the fibers and the skin during cleansing. In the instancewhere the lotion comprises a hydrophilic ingredient that is to beimparted to the skin during cleansing, the use of hydrophobic fibers inthe substrate favors the partitioning, and subsequent delivery, of thehydrophilic ingredient to the skin.

Hydrophobic fibers can be any material, such as, but not limited to,those selected from the group consisting of polyesters (e.g.,polyethylene terephthalate), polyolefins, polypropylenes, polyethylenes,polyethers, polyamides, polyesteramides, and combinations thereof.Further, the hydrophobic fibers can be a single component (i.e., singlesynthetic material or mixture makes up entire fiber), bi-component(i.e., the fiber is divided into regions, the regions including two ormore different synthetic materials or mixtures thereof and may includeco-extruded fibers and core and sheath fibers) and combinations thereof.

The fibers may be circular in cross-section, dog-bone shape, delta(i.e., triangular cross section), trilobal, ribbon, or other shapestypically produced as staple fibers. Likewise, the fibers can beconjugate fibers such as bicomponent fibers. The fibers may be crimpedand may have a finish, such as a lubricant, applied.

The substrate materials may also be treated to improve the softness andtexture thereof. The substrate may be subjected to various treatments,such as, but not limited to, physical treatment, such as hydro-molding,hydro-embossing, ring rolling, as described in U.S. Pat. No. 5,143,679issued to Weber et al. on Sep. 1, 1992; structural elongation, asdescribed in U.S. Pat. No. 5,518,801 issued to Chappell et al. on May21, 1996; consolidation, as described in U.S. Pat. No. 5,914,084 issuedto Benson et al. on Jun. 22, 1999; U.S. Pat. No. 6,114,263 issued toBenson et al. on Sep. 5, 2000; U.S. Pat. No. 6,129,801 issued to Bensonet al. on Oct. 10, 2000 and U.S. Pat. No. 6,383,431 issued to Dobrin etal. on May 7, 2002; stretch aperturing, as described in U.S. Pat. No.5,628,097 issued to Benson et al. on May 13, 1997; U.S. Pat. No.5,658,639 issued to Curro et al. on Aug. 19, 1997 and U.S. Pat. No.5,916,661 issued to Benson et al. on Jun. 29, 1999; differentialelongation, as described in US Publication No. 2003/0028165A1 publishedon Feb. 6, 2003 by Curro et al.; and other solid state formationtechnologies as described in U.S. Publication No. 2004/0131820A1published on Jul. 8, 2004 by Turner et al. and U.S. Publication No.2004/0265534A1 published on Dec. 30, 2004 by Curro et al., zoneactivation, and the like; chemical treatment, such as, but not limitedto, rendering part or all of the substrate hydrophobic, and/orhydrophilic, and the like; thermal treatment, such as, but not limitedto, thermal-embossing, softening of fibers by heating, thermal bondingand the like; and combinations thereof.

Without being bound by theory, it is believed that a textured substratemay further enable the ease of removal of the bodily exudates byimproving the ability to grip or otherwise lift the exudates from theskin during cleansing. Any one of a number of texture elements may beuseful in improving the ability to grip or otherwise lift the exudatesfrom the skin during cleansing such as, but not limited to continuoushydro-molded elements, hollow molded element, solid molded elements,circles, squares, rectangles, ovals, ellipses, irregular circles,swirls, curly cues, cross hatches, pebbles, lined circles, linkedirregular circles, half circles, wavy lines, bubble lines, puzzles,leaves, outlined leaves, plates, connected circles, changing curves,dots, honeycombs, etc. and combinations thereof. The texture elementsmay be hollow elements. The texture elements may be connected to eachother. The texture elements may overlap each other.

The substrate may have a basis weight between about 15, 30, 40 or 45grams/m² and about 65, 75, 85, 95 or 100 grams/m². A suitable substratemay be a carded nonwoven comprising a 40/60 blend of viscose fibers andpolypropylene fibers having a basis weight of 58 grams/m² as availablefrom Suominen of Tampere, Finland as FIBRELLA™ 3160. FIBRELLA™ 3160 is a58 grams/m² nonwoven web comprising 60% w/w 1.5 denier polypropylenefibers and 40% w/w 1.5 denier viscose fibers. Another suitable materialmay be FIBRELLA™ 3100 which is a 62 grams/m² nonwoven web comprising 50%w/w 1.5 denier polypropylene fibers and 50% w/w 1.5 denier viscosefibers. In both of these commercially available fibrous webs, theaverage fiber length is about 38 mm. Another suitable material for useas a substrate may be SAWATEX™ 2642 as available from Sandler AG ofSchwarzenbach/Salle, Germany. Yet another suitable material for use as asubstrate may have a basis weight of from about 50 grams/m² to about 60grams/m² and have a 20/80 blend of viscose fibers and polypropylenefibers. The substrate may also be a 60/40 blend of pulp and viscosefibers.

In one embodiment, the surface of the substrate may be essentially flat.In another embodiment, the surface of the substrate may optionallycontain raised and/or lowered portions. These can be in the form oflogos, indicia, trademarks, geometric patterns, images of the surfacesthat the substrate is intended to clean (i.e., infant's body, face,etc.). They may be randomly arranged on the surface of the substrate orbe in a repetitive pattern of some form.

In another embodiment, the substrate may be biodegradable. For examplethe substrate could be made from a biodegradable material such as apolyesteramide, or a high wet strength cellulose.

Lotion

“Lotion,” as used herein, refers to a composition comprising a carriersuch as water. The lotion further comprises an anti-stick agent.Additional optional ingredients may be added to the lotion as desired,as described herein, to form a lotion composition. The lotion may form afilm on the surface of the skin and may provide increased repellency ofresidual soils or exudates at a low level of anti-stick agent.

Anti-Stick Agent

As used herein, the term “anti-stick agent” refers to water-solublematerials which may help reduce or prevent the adherence of soils orexudates to bodily surfaces, thereby facilitating subsequent cleanings.“Soils” refers herein to material from a source extraneous to the body,such as dirt and food. “Exudates” refers herein to material from asource internal to the body, such as urine, menses, feces, and mucus.

Without being bound by theory, it is believed that anti-stick agents mayreduce the adhesive force between the soils or exudates and the skinsurface such that the adhesive forces may be smaller than the cohesiveforces within the soils or exudates, thereby allowing the soils orexudates to detach from the skin surface upon application of a shearforce such as that generated by wiping. It is not intended that thismechanism describe the means by which all anti-stick agents describedherein function. Other possible mechanisms of reducing adhesion to skinwill be obvious to those skilled in the art.

The use of non-water soluble materials to reduce adhesion of soils orexudates to skin is known in the art. Materials such as silicones,mineral oil, petrolatum, plant-derived oils, and other hydrophobicemollients are known in wet wipes in the form of emulsions. Examples ofsuch emulsions may be found in U.S. Pat. No. 6,083,854 issued Jul. 4,2000 to Bogdanski et al; U.S. Pat. No. 5,648,083 issued Jul. 15, 1997 toBlieszner et al.; and U.S. Pat. No. 6,440,437 issued Aug. 27, 2002 toKrzysik et al.

While non-water soluble materials such as those described above maydeliver some level of anti-stick performance, they suffer from severalmajor setbacks including:

-   -   they often leave an undesirable greasy or slippery feel on the        skin, and    -   they are typically lubricious, reducing interaction of the        cleansing implement and the soils or exudates, resulting in        smearing and poor cleaning.

Water soluble anti-stick agents overcome many of these setbacks. For thepurposes of the present invention, an anti-stick agent is consideredwater soluble if about 0.01%, 0.1%, 0.5%, or 1.0% w/w or greaterdissolves in water at 25° C. Water soluble anti-stick agents may havethe following advantages:

-   -   they typically do not leave a greasy feeling on the skin, and    -   they are typically not as lubricous as non-water soluble        anti-stick agents and may result in better cleaning and less        smearing.

There is a further need for a substrate that may in contact with alotion that may deliver good repellency of soils or exudates whileutilizing low concentration levels of anti-stick agent, such as lessthan or equal to about 10% w/w concentration of anti-stick agent in thelotion. Such a lotioned substrate may be cost effective due to thedecreased amount of anti-stick agent required to deliver the benefit anddue to the ease of incorporation of the anti-stick agent into the lotiondue to the water solubility of the anti-stick agent. Further, theanti-stick agent may result in a cleansing benefit such as therepellency of soils or exudates and may result in no sensory negativeson the skin such as a greasy or slippery film. Consumers may prefer asubstrate that can deliver an anti-stick benefit while being used forroutine cleansing, i.e. consumers may not prefer an additional step tothe process of cleansing, such as the use of one substrate to clean andthe use of an additional substrate that cleans poorly but provides theanti-stick benefit. An example of a wipe containing a hydrophobicanti-stick agent that cleans poorly and needs to be used as a separatewipe is described in US 2005/0244480A1.

The strength of adhesion between two materials may be analyzed in avariety of methods to determine whether or not the adhesive interactionsare impacted by surface treatments or other factors. Examples ofadhesion tests for determining if a treatment has reduced adhesionbetween two materials (such as by reducing the force of adhesion to lessthan the force of cohesion) include ASTM D2919, ASTM D3528 and relatedmethods referred to or described therein. Such methods may test thestrength of adhesion through the application of shear.

A method for assessing the adhesion of soils or exudates to the skinsurface has been detailed herein. It has been discovered that someanti-stick agents, used at a low level (e.g., in a lotion), may providean anti-stick benefit on skin, but the magnitude of this anti-stickbenefit is greatly reduced on artificial surfaces. Without being boundby theory, it is believed that factors such as the wettability, surfaceenergy, and surface chemistry of skin are critical for the formation ofeffective anti-stick films containing certain water soluble anti-stickagents.

The test for assessing the adhesion of soils or exudates to the skin isdescribed in detail in the TEST METHODS section. Briefly, the Anti-StickScreening Method treats the skin surface with a defined amount ofanti-stick agent or a lotion comprising the anti-stick agent. A definedamount of an artificial pasty bowel movement (“ABM”) is applied. The ABMis covered with a square piece of paper, and compressed with a definedforce for a defined amount of time. The paper is then peeled away slowlywith forceps. The paper is tared before application of the ABM and isre-weighed after removal from the skin. The percent residual ABM on theskin is calculated as the weight of the artificial bowel movement (ABM)remaining on the skin versus the weight of the artificial bowel movementoriginally applied to the skin. The ABM, similar to real infant BM,fails cohesively, resulting in part of the ABM remaining on the skinsurface and part of the ABM remaining on the piece of paper. The moreefficient the anti-stick agent or lotion comprising the anti-stickagent, the less residual ABM on the skin surface. While artificial ABMis utilized in the Anti-Stick Screening Method, the artificial ABM maycorrelate in physical properties to soils or exudates. The percentresidual artificial ABM may, therefore, be utilized as an equivalentmeasurement of the percent residual soils or exudates.

An anti-stick agent beneficial for use may leave less than about 10%,8%, 7%, 5%, 4%, 3% or 2% residual soils or exudates on the skin surfaceas assessed by the Anti-Stick Screening Method. Skin that is not treatedwith an anti-stick agent, either alone or within a lotion, but isotherwise subjected to the above method may serve as a negative control.Typically, no treatment of the skin results in about 30-35% residualsoils or exudates remaining on the skin surface.

Conventional substrates comprising a lotion, both aqueous-based andemulsion-based, may deliver anti-stick performance in the range of about15-30% residual soils or exudates in the above method. It has beendiscovered that this level of performance is insufficient to deliver aconsumer noticeable anti-stick benefit.

The lotion of the present invention may comprise at least about 0.05%w/w of an anti-stick agent. The lotion may comprise equal to or lessthan about 50% w/w of an anti-stick agent. The lotion may comprise ananti-stick agent at a level from about 0.05%, 0.1%, 0.5%, 1%, 2%, 4% or5% to about 8%, 10%, 20%, 25% or 50% w/w of the lotion composition. Thelotion comprising an anti-stick agent may be effective at leaving lessthan about 10% residual soils or exudates on the skin as measured by theAnti-Stick Screening Method as described herein. Such a lotion may leaveless than about 2%, 3%, 4%, 5%, 7%, 8% or 10% residual soils or exudatesremaining on the skin. The anti-stick agent may be present in a lotionat a level of about 1% w/w wherein the lotion may leave less than about10% residual soils or exudates on the skin. In another embodiment, theanti-stick agent may be present in a lotion at a level of about 2% w/wand may leave less than about 5% or 10% residual soils or exudates onthe skin. The lotion comprising the anti-stick agent, as describedherein, may be in contact with a substrate to form a lotioned wipeproduct. The lotioned wipe product may also be effective at leaving lessthan about 10%, 8%, 7%, 5%, 4%, 3%, or 2% residual soils or exudates onthe skin.

Water-soluble anti-stick agents include, but are not limited to:

-   -   Non-polymeric anti-stick agents such as glycerol and related        polyols such as sorbitol, maltitol, xylitol, pentaerythitol,        sucrose, glucose, maltose, maltotriose, maltodextrin,        maltopentose, maltohexose, and isomaltulose, ethylene glycol,        propylene glycol, butylene glycol, and the like.    -   Polymeric anti-stick agents comprising polyethylene glycol,        polypropylene glycol, polybutylene glycol, polyglycerol or        mixtures thereof, including block copolymers comprising ethylene        oxide and propylene oxide, and the like.    -   Silicone copolyols comprising polyethylene glycol, polypropylene        glycol, polybutylene glycol, polyglycerol or mixtures thereof,        and the like.    -   Mono-functional heteroatom oxide ethers of polyethylene glycol,        polypropylene glycol, polybutylene glycol, polyglycerol or        mixtures thereof, and homologues and derivatives thereof.    -   Poly-functional heteroatom oxide esters of polyethylene glycol,        polypropylene glycol, polybutylene glycol, polyglycerol or        mixtures thereof, and homologues and derivatives thereof.        and combinations of the above.        Non-Polymeric Anti-Stick Agents:

Non-polymeric anti-stick agents, such as those listed above, may providean anti-stick benefit. Non-polymeric anti-stick agents may be requiredat relatively high levels in the composition relative to polymericanti-stick agents. In one embodiment, a lotion comprising glycerol at alevel of about 50% w/w may leave less than about 10% residual soils orexudates on the skin.

Polymeric Anti-Stick Agents:

Polymeric anti-stick agents comprising polyethylene glycol,polypropylene glycol, polybutylene glycol, polyglycerol or mixturesthereof, including block copolymers comprising ethylene oxide andpropylene oxide, have been found to be useful as anti-stick agents.Commercially available examples of polymeric anti-stick agents includethe Carbowax™ and Polyox™ series as available from The Dow ChemicalCompany of Midland, Mich., and the Pluronic™, Pluronic™ R, Tetronic™,and Tetronic™ R surfactant series as available from BASF Corporation ofFlorham Park, N.J. In one embodiment, a lotion comprising Carbowax 400at a level from about 20% or 25% to about 50% w/w may leave less thanabout 5%, 3% or 2% residual soils or exudates on the skin.

Silicone Copolyols:

Water soluble silicone copolyols, also known as silicone polyethers,have also been found to deliver an anti-stick benefit. Commerciallyavailable examples of water soluble silicone copolyols include membersof the Silwet™ and Silsoft™ series as available from GE Silicones ofWilton, Conn., members of the ABIL™ B and ABIL™ Care series as availablefrom Goldschmidt GmbH of Essen, Germany, and members of the Belsil™series as available from Wacker Chemie GmbH of Burghausen, Germany. FIG.1 is an illustration of the general structure to which siliconecopolyols may conform wherein:

-   x is a number from about 5 to about 50,-   y is a number from about 3 to about 10,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof, and-   D is polyoxyethylene, polyoxypropylene, polyglycerol or combinations    thereof as exemplified in FIG. 2.-   In certain embodiments of D,-   e is a number from about 10 to about 30,-   p is a number from about 0 to about 10, and-   g is about 0-   it being understood that:-   x/y is less than about 10 and may be less than or equal to about 8,-   e+p is less than about 30 and may be less than or equal to about 20,-   e/p is greater than about 1 and may be greater than or equal to    about 4, and-   x+y is less than about 60 and may be less than about 40.

The synthesis of the silicone copolyols may result in a mixture ofdifferent chain lengths in each of the polymer blocks and may thereforeresult in an average of different chain lengths. In one embodiment theaverage of these different chain lengths are x=9.5, y=3.5, e=11.5,p=2.5, and R is a hydrogen atom. In another embodiment the average ofthese different chain lengths are x=14, y=4, e=17, p=1, and R is ahydrogen atom. In yet another embodiment the average of these differentchain lengths are x=48, y=6, e=15, p=5, and R is a hydrogen atom. Itshould be understood that x and y may be an average of chain lengths.

In one embodiment, a lotion comprising a silicone polyether, such asDV7425, which is available from Rhodia Inc. of Bristol, Pa., at a levelfrom about 4% or 5% to about 8% or 9% w/w may leave less than about 10%,7%, 5%, 3%, or 2% residual soils or exudates on the skin.

Mono-Functional Heteroatom Oxide Ethers and Homologues and DerivativesThereof:

Mono-functional heteroatom oxide ethoxylated ethers have also been foundto deliver an anti-stick benefit. FIG. 3 is an illustration of thegeneral structure to which mono-functional heteroatom oxide ethoxylatedethers may conform wherein:

-   A is a heteroatom oxide selected from the group consisting of    phosphonate, sulphonate, carbonate,-   M is selected from the group consisting of a hydrogen, any inorganic    cation (e.g. Na⁺, NH4⁺), organic cation, and combinations thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof,-   k is a number from about 2 to about 5,-   m is a number from about 2 to about 5,-   n is a number from about 2 to about 3,-   x is a number from about 0 to about 25, and-   y is number from about 0 to about 25.

FIG. 4 is an illustration of the general structure to whichmono-functional phosphonate ethoxylated ethers may conform wherein:

-   M is selected from the group consisting of a hydrogen, any inorganic    cation (e.g. Na⁺, NH4⁺), organic cation, and combinations thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof,-   k is a number from about 2 to about 5,-   m is a number from about 2 to about 5,-   n is a number from about 2 to about 3,-   x is a number from about 0 to about 25, and-   y is number from about 0 to about 25.

In one embodiment, a lotion comprising a 1-phosphonate ethoxylate, suchas DV7436, which is available from Rhodia Inc. of Bristol, Pa., at alevel from about 4% or 5% to about 7% or 8% w/w may leave less thanabout 5%, 4% or 3% residual soils or exudates on the skin.

FIG. 5 is an illustration of the general structure to whichmono-functional carbonato ethoxylated ethers may conform wherein:

-   M is a hydrogen, any inorganic cation (e.g. Na⁺, NH4⁺), organic    cation, or combinations thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof,-   k is a number from about 2 to about 5,-   m is a number from about 2 to about 5,-   n is a number from about 2 to about 3,-   x is a number from about 0 to about 25, and-   y is number from about 0 to about 25.

FIG. 6 is an illustration of the general structure to whichmono-functional sulphonato ethoxylated ethers may conform wherein:

-   M is a hydrogen, any inorganic cation (e.g. Na⁺, NH4⁺), organic    cation, or combinations thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof,-   k is a number from about 2 to about 5,-   m is a number from about 2 to about 5,-   n is a number from about 2 to about 3,-   x is a number from about 0 to about 25, and-   y is number from about 0 to about 25.    Poly-Functional Heteroatom Oxide Esters and Homologues and    Derivatives Thereof:

FIG. 7 is an illustration of the general structure to whichpoly-functional heteroatom oxide esters may conform wherein:

-   A is a heteroatom oxide selected from the group consisting of    phosphonate, phosphate, phosphite, sulphonate, sulfite, sulfate,    borate and combinations thereof,-   D is polyoxyethylene, polyoxypropylene, polyglycerol or a    combination thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof, or PO₃-M₂,-   M is a hydrogen, any inorganic cation (e.g. Na⁺, NH4⁺), organic    cation, or combinations thereof, and-   The poly-functional heteroatom oxide ester is a mixture of molecules    with n=from about 1 to about 5, with the number average of this    mixture being from about 1.05 to about 1.97.

FIG. 8 is an illustration of the general structure to whichpoly-functional phosphate esters may conform wherein:

-   D is polyoxyethylene, polyoxypropylene, polyglycerol or combinations    thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof, or PO₃-M₂,-   M is a hydrogen, any inorganic cation (e.g. Na⁺, NH4⁺), organic    cation, or combination thereof, and-   The poly-functional phosphate ester is a mixture of molecules with    n=from about 1 to about 5, with the number average of this mixture    being from about 1.05 to about 1.97.

In one embodiment, a lotion comprising a PEG400 phosphate ester or aPEG600 phosphate ester, such as DV7656 or DV7658 respectively, which areavailable from Rhodia Inc. of Bristol, Pa., at a level from about 1% or2% to about 4% w/w may leave less than about 10%, 7%, 5%, 4% or 3%residual soils or exudates on the skin. In another embodiment, a lotioncomprising a PPG425 phosphate ester, such as DV8094, which is availablefrom Rhodia Inc. of Bristol, Pa., at a level from about 1% or 2% toabout 4% w/w may leave less than about 8%, 5%, 4%, or 3% residual soilsor exudates on the skin. In yet another embodiment, a lotion comprisinga PPG425/PEG400 phosphate ester, such as DV8097, which is available fromRhodia Inc. of Bristol, Pa., at a level from about 1% or 2% to about 4%w/w may leave less than about 10%, 8%, 6%, 4%, or 3% residual soils orexudates on the skin.

FIG. 9 is an illustration of the general structure to whichpoly-functional sulfate esters may conform wherein:

-   D is polyoxyethylene, polyoxypropylene, polyglycerol or combinations    thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof, or SO₄-M₂,-   M is a hydrogen, any inorganic cation (e.g. Na⁺, NH4⁺), organic    cation, or combinations thereof, and-   The poly-functional sulfate ester is a mixture of molecules with    n=from about 1 to about 5, with the number average of this mixture    being from about 1.05 to about 1.97.

FIG. 10 is an illustration of the general structure to whichpoly-functional sulphonate esters may conform wherein:

-   D is polyoxyethylene, polyoxypropylene, polyglycerol or combinations    thereof,-   R is a hydrogen, a hydrocarbyl (including aliphatic and aromatic), a    linear or branched alkyl radical containing from 1 to 22 carbon    atoms, a linear or branched alkyl radical containing from 1 to 4    carbon atoms, an acetyl group, and combinations thereof, or SO₃-M₂,-   M is a hydrogen, any inorganic cation (e.g. Na⁺, NH4⁺), organic    cation, or combinations thereof, and-   The poly-functional sulphonate ester is a mixture of molecules with    n=from about 1 to about 5, with the number average of this mixture    being from about 1.05 to about 1.97.    Optional Lotion Ingredients

Additional ingredients may be added to the lotion as desired to create alotion composition. The composition may generally comprise any of thefollowing ingredients: emollients, surfactants, rheology modifiers,preservatives, or a combination of preservative compounds actingtogether as a preservative system or other adjunct ingredients. It is tobe noted that some ingredient compounds can have a multiple function andthat all compounds are not necessarily present in the composition. Thecomposition may be an aqueous-based solution or an emulsion. The pH ofthe composition may be from about pH 3, 4, or 5 to about pH 7, 7.5, or8.

Examples of lotions and lotion compositions that may be used may befound in the Examples section as Examples 1 through 32.

Emollient

Emollients may (1) improve the glide of the substrate on the skin, byenhancing the lubrication and thus decreasing the abrasion of the skin,(2) hydrate the residues (for example, fecal residues or dried urineresidues or menses), thus enhancing their removal from the skin, (3)hydrate the skin, thus reducing its dryness and irritation whileimproving its flexibility under the wiping movement, and (4) protect theskin from later irritation (for example, caused by the friction of anabsorbent article) as the emollient is deposited onto the skin andremains at its surface as a thin protective layer.

Emollients may include silicone oils, functionalized silicone oils,hydrocarbon oils, fatty alcohols, fatty alcohol ethers, fatty acids,esters of monobasic and/or dibasic and/or tribasic and/or polybasiccarboxylic acids with mono and polyhydric alcohols, polyoxyethylenes,polyoxypropylenes, mixtures of polyoxyethylene and polyoxypropyleneethers of fatty alcohols, and mixtures thereof. The emollients may beeither saturated or unsaturated, have an aliphatic character and bestraight or branched chained or contain alicyclic or aromatic rings.

A useful mixture of emollients is caprylic capric triglycerides incombination with Bis-PEG/PPG-16/16 PEG/PPG-16/16 dimethicone known asABIL CARE™ 85 (available from Degussa Care Specialties of Hopewell,Va.).

Emollients, when present, may be used in the present invention at aweight/weight % from about 0.5%, 1% or 4% to about 0.001%, 0.01%, or0.02% w/w. Without being bound by theory, it is believed that low levelsof emollients are desirable as this may reduce the tendency of theemollients to form a greasy or oily layer on the skin, which may not beconsumer preferred.

Surfactant

The surfactant can be an individual surfactant or a mixture ofsurfactants. The surfactant may be a polymeric surfactant or anon-polymeric one. The surfactant may be employed as an emulsifier. Thesurfactant, when present, may be employed in an amount effective toemulsify the emollient and any other non-water-soluble oils that may bepresent in the composition, such as an amount ranging from about 0.5%,1%, or 4% w/w to about 0.001%, 0.01% or 0.02% w/w (based on the weightsurfactant over the weight of the composition).

The composition may include one or more surfactants. The surfactant orcombinations of surfactants may be mild, which means that thesurfactants provide sufficient cleansing or detersive benefits but donot overly dry or otherwise harm or damage the skin.

A wide variety of surfactants are useful herein and include thoseselected from the group consisting of anionic surfactants, nonionicsurfactants, cationic surfactants, amphoteric surfactants, zwitterionicsurfactants, and mixtures thereof.

A wide variety of anionic surfactants are useful herein. Non-limitingexamples of anionic surfactants include those selected from the groupconsisting of sarcosinates, sulfates, sulfonates, isethionates,taurates, phosphates, lactylates, glutamates, and mixtures thereof.Amongst the isethionates, the alkoyl isethionates are useful, andamongst the sulfates, the alkyl and alkyl ether sulfates are useful.Other anionic materials useful herein are soaps (i.e., alkali metal oramine salts, e.g., sodium, potassium or triethanol amine salts) of fattyacids, typically having from about 8 to about 24 carbon atoms.

Nonionic surfactants useful herein include, but are not limited to,those selected from the group consisting of alkyl glucosides, alkylpolyglucosides, polyhydroxy fatty acid amides, alkoxylated fatty acidesters, alkoxylated fatty alcohol ethers, sucrose esters, amine oxides,and mixtures thereof.

Suitable amphoteric or zwitterionic surfactants for use in thecompositions herein include those which are known for use in hair careor other personal care cleansing. Amphoteric surfactants suitable foruse in the present compositions are well known in the art and includethose surfactants broadly described as derivatives of aliphaticsecondary and tertiary amines in which the aliphatic radical can bestraight or branched chain and wherein one of the aliphatic substituentscontains from about 8 to about 18 carbon atoms and one contains ananionic water solubilizing group such as carboxy, sulfonate, sulfate,phosphate, or phosphonate. Useful amphoteric surfactants include, butare not limited to, the group consisting of cocoamphoacetate,cocoamphodiacetate, lauroamphoacetate, lauroamphodiacetate, and mixturesthereof.

Zwitterionic surfactants suitable for use herein include thosesurfactants broadly described as derivatives of aliphatic quaternaryammonium, phosphonium, and sulfonium compounds, in which the aliphaticradicals can be straight or branched chain, and wherein one of thealiphatic substituents contains from about 8 to about 18 carbon atomsand one contains an anionic group such as carboxy, sulfonate, sulfate,phosphate or phosphonate. Useful zwitterionic detersive surfactants arethe betaines, amphoacetates and sulfobetaines, e.g.,cocoamidopropylbetaine, sodiumlaurylamphoacetate andcocoamidopropylhydroxysultaine.

Rheology Modifier

Rheology modifiers are compounds that increase the viscosity of thelotion composition. These materials may also provide “structure” to thecompositions to prevent settling out (separation) of insoluble andpartially soluble components.

The rheology modifier, in addition to stabilizing the suspension ofinsoluble and partially soluble components, may also (1) help tostabilize the lotion composition on a substrate, (2) enhance thetransfer of the lotion composition to the skin, and (3) enhance theuniformity of the layer of the lotion composition on the skin.

Rheology modifiers may also affect the rheological profile of the lotioncomposition such that the viscosity of the lotion composition may changeas a function of the shear that is applied to the lotion composition.The application of the lotion composition to a surface (e.g. the skin)typically includes a “wiping” or “rubbing” movement. This movement mayincrease the shear and pressure experienced by the lotion composition.In the case of a shear-thinning rheological profile (i.e. an increase inshear reduces the viscosity of the lotion composition), the viscosity ofthe lotion may decrease with the increased shear of “wiping” or“rubbing” thereby enabling a better transfer to the skin as well as abetter lubrication effect.

Additionally, the rheology modifier may help to preserve a homogeneousdistribution of the lotion composition within a stack of the substrates.Any composition that is in fluid form may have a tendency to migrate tothe lower part of the wipes stack during prolonged storage. This effectmay create an upper part of the stack of substrates having less lotioncomposition than the bottom part of the stack.

Examples of rheology modifiers include, but are not limited to,Ultrez™-10, a carbomer, and Pemulen™ TR-2, an acrylate crosspolymer,both of which are available from Noveon, Cleveland Ohio, and Keltrol™, aXanthan gum, available from CP Kelco, San Diego Calif., and combinationsthereof.

Rheology modifiers, when present, may be used at a weight/weight % (w/w)from about 0.01%, 0.015%, or 0.02% to about 1%, 2% or 3%.

Preservative

Controlling microbiological growth may be beneficial in water basedproducts such as lotion compositions intended for application tosubstrates in forming wipes. The lotion composition may comprise apreservative or a combination of preservatives acting together as apreservative system. Preservatives and preservative systems are usedinterchangeably in the present document to indicate one unique or acombination of preservative compounds. A preservative may be understoodto be a chemical or natural compound or a combination of compoundsreducing the growth of microorganisms, thus enabling a longer shelf lifefor a package of substrates (opened or not opened) as well as creatingan environment with reduced growth of microorganisms when transferred tothe skin during the wiping process.

The spectrum of activity of the preservative may include bacteria, moldsand yeast. Each of such microorganisms may be killed by thepreservative. Another mode of action to be contemplated may be thereduction of the growth rate of the microorganisms without activekilling. Both actions however result in a drastic reduction of thepopulation of microorganisms.

Materials useful as preservatives include, but are not limited to:methylol compounds, iodopropynyl compounds, simple aromatic alcohols,paraben compounds, chelators such as ethylenediamine tetraacetic acid,and combinations thereof.

In one embodiment, the preservative system may comprise a methylolcompound or its equivalent, an iodopropynyl compound and mixturesthereof. Methylol compounds may release a low level of formaldehyde whenin a water solution that has an effective preservative activity.Exemplary methylol compounds include, but are not limited to,diazolidinyl urea (GERMALL® II as is available from InternationalSpecialty Products of Wayne, N.J.),N-[1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N′-bis(hydroxymethyl)urea,imidurea (GERMALL® 115 as is available from International SpecialtyProducts of Wayne, N.J.), 1,1-methylenebis[3-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea],1,3-dimethylol-5,5-dimethyl hydantoin (DMDMH), sodium hydroxymethylglycinate (SUTTOCIDE® A as is available from International SpecialtyProducts of Wayne, N.J.), and glycine anhydride dimethylol (GADM).Methylol compounds can be used at concentrations between about 0.025%and about 0.50% w/w. In another embodiment, the concentration may beabout 0.075% w/w. The iodopropynyl compound may provide antifungalactivity. An exemplary material may be iodopropynyl butyl carbamate asis available from Clariant UK, Ltd. of Leeds, The United Kingdom asNIPACIDE™ IPBC. Another exemplary material may be3-iodo-2-propynylbutylcarbamate. Iodopropynyl compounds can be usedeffectively at a concentration between about 0.001% and about 0.05% w/w.The concentration may be about 0.009% w/w. A preservative system of thistype may comprise a blend of a methylol compound at a concentration ofabout 0.075% w/w and an iodopropynyl compound at a concentration ofabout 0.009% w/w.

In another embodiment, the preservative system may comprise simplearomatic alcohols (e.g. benzyl alcohol). Materials of this type may haveeffective antibacterial activity. Benzyl alcohol is available fromSymrise, Inc. of Teterboro, N.J.

In another embodiment, the preservative may comprise at least oneparaben antimicrobial. The preservative may be a paraben antimicrobialselected from the group consisting of methylparaben, ethylparaben,propylparaben, butylparaben, isobutylparaben or combinations thereof.The total concentration of paraben antimicrobial may be lower than about0.3%, 0.5%, or 1% w/w. The minimum amount of paraben antimicrobial maybe any amount sufficient to obtain the desired preservation of thecomposition, such as more than about 0.001%.

In another embodiment, acidic compounds used in sufficient amount toreduce the pH of the lotion composition (e.g. pH of less than about 5)may be useful as the preservative, or as a potentiator for otherpreservative ingredients.

In another embodiment, chelators, such as ethylenediamine tetraaceticacid and its salts, may also be used in preservative systems as apotentiator for other preservative ingredients.

Adjunct Ingredients

The lotion composition may optionally include other adjunct ingredients.Possible adjunct ingredients may be selected from a wide range ofadditional ingredients such as, but not limited to perfumes andfragrances, texturizers, colorants, soothing agents and medically activeingredients, such as healing actives and skin protectants.

Article of Commerce

In one embodiment, an article of commerce may be provided. The articleof commerce may comprise a container as described herein and at leastone substrate as described herein.

Containers useful may include, but are not limited to, PET tubs, flowwrap pouches, precut sachets for individually packed cleansing mitts,and other packaging known in the art as suitable for nonwoven articles.Additionally, the container may also be manufactured to facilitateremoval of individual cleansing substrates.

The container may be made of any suitable material or materials and canbe manufactured in any suitable manner. For example, the container canbe made of polystyrene, polypropylene, PET, POET, polyethylene,polyester, polyvinyl alcohol, or the like. The containers may also bemade of a mixture of the above materials. The containers may bemanufactured by, for example, a vacuum molding process or an injectionmolding process, or any suitable process.

Additional information on containers, as well as additional optionalcomponents for containers, including, but not limited to: containerbodies, lids, container features, such as, but not limited to,attachment of lids, hinges, zippers, securing aids, and the like, can befound in U.S. Pat. No. Des. 451,279; Des. 437,686; Des. 443,508; Des443,451; Des 421,901; Des 421,902; Des 416,794; Des 414,637; Des445,329; 3,982,659; 3,967,756; 3,986,479; 3,994,417; 6,269,970;5,785,179; 5,366,104; 5,322,178; 5,050,737; 4,971,220; 6,296,144;6,315,114; 4,840,270; 4,471,881; 5,647,506; 6,401,968; 6,269,969;6,412,634; 5,791,465; 6,092,690; U.S. Patent Application Publication No.2002/0064323 published on May 30, 2002, issued to Chin; and WO 00/27268published on May 18, 2000 and assigned to The Procter & Gamble Company;WO 02/14172 published on Feb. 21, 2002 and assigned to The Procter &Gamble Company; and WO 99/55213 published on Nov. 4, 1999 and assignedto The Procter & Gamble Company.

Anti-Stick Screening Method

This method may be used for assessing the adhesion of soils or exudatesto the skin by quantifying the percentage of residual artificial pastybowel movement (“ABM”) left on the skin surface after treatment. TheABM, similar to real infant BM, fails cohesively, resulting in part ofthe ABM remaining on the skin surface and part of the ABM being removed.The more efficient the anti-stick agent or lotion comprising theanti-stick agent, the lower the percentage of residual ABM on the skinsurface.

At least eight healthy adults participate in a single screening study.Each of the panelists completes a four-day washout period during whichthey use Olay® unscented moisturizing soap, as distributed by TheProcter and Gamble Company, Cincinnati, Ohio, to wash their forearms.Panelists must refrain from using any topical product, such asointments, creams or lotions, on their forearms during this washout-outperiod and also on the day of the screening study. On the day oftesting, panelist's arms are inspected to ensure they are free of cuts,scratches, and rashes. If any skin abnormalities are present, thepanelist cannot participate.

A template and a fine-tip marker are used to mark-off up to ten 3 cm by3 cm sites on the volar forearms, i.e. up to ten sites per panelist. Allbut one of these sites are treated with an anti-stick agent or a lotioncomprising an anti-stick agent. The remaining site receives noanti-stick treatment, i.e. serves as a negative control. The locationsof the various treatments, including the no-treatment site, may berandomized among the sites on each panelist. Testing starts at the siteclosest to the elbow on the left arm and, as testing on each site iscompleted, progresses to the site closest to the wrist on the left arm,then to the site closest to the elbow on the right arm, and finally tothe site closest to the wrist on the right arm. Testing on each siterequires approximately 4 minutes, for a total time per panelist ofapproximately 40 minutes.

For each site that is treated, 1 μl/cm² or 9 μl/site of anti-stick agentor lotion comprising an anti-stick agent is applied in the center of thesite using a standard or positive displacement pipettor. The appliedagent or lotion is then spread over the entire site (the boundary ofwhich is defined by the marks made using the template) using apowder-free finger cot, Catalog #56613-413 as available from VWRScientific of West Chester, Pa., by placing the finger cot on top of theagent or lotion droplet and lightly rubbing the finger cot over the skinsurface using several side-to-side and up-and-down movements for a totalelapsed time of 10-15 seconds. Examining the site from an oblique angle,the person conducting the test needs to ensure that a uniform film hasbeen formed over the entire area of the site. The film is left exposedto air, untouched, for approximately 1 minute prior to proceeding withthe subsequent steps.

A 1 ml syringe, such as Catalog #BD-309628 as available from VWRScientific of West Chester, Pa., that has been filled with roomtemperature ABM and is devoid of air bubbles, is placed onto a taredfour-place analytical balance. The weight is recorded. The syringe withABM is held over the center of the test site on the forearm, inreasonably close proximity to the skin surface, and approximately 0.2 mlof ABM is dispensed onto the skin by pressing the plunger and bywatching the gradations on the syringe. The ABM should form a reasonablyuniform, compact mound in the center of the test site. The syringe isre-weighed on the analytical balance, and the weight is recorded. Thequantity of ABM that was delivered to the forearm is calculated bysubtracting the second weight from the first.

A 4 cm×4 cm piece of weigh paper, Catalog #12578-201 as available fromVWR Scientific of West Chester, Pa., is tared on the four placeanalytical balance, centered over the ABM mound on the forearm testsite, and gently lowered onto the ABM using forceps. The weigh papermust not be touched with fingertips, as this may transfer oils onto itssurface. Next, a 500 g bottle-shaped weight, such as Catalog #12766-518as available from VWR Scientific of West Chester, Pa., that exertsapproximately 0.5 psi of downward force is placed over the weigh papersuch that the mound of ABM under the weigh paper is approximatelycentered under the weight. The weight may be gently held in place orbalanced on the forearm by the panelist for 30 seconds. After 30 secondshave elapsed, two fingers are placed gently on either side of the weighpaper to hold it in place, and the 500 g weight is slowly lifted. Usinga pair of forceps, the weigh paper is slowly and gently peeled from thetest site. The forceps are placed at the lower right corner of the weighpaper, and the weigh paper is slowly peeled upwards in the direction ofthe upper left corner of the weigh paper. It should take approximately1-2 seconds to remove the weigh paper. Once removed, the weigh paper isplaced back onto the analytical balance that it was tared on, and theweight is recorded to determine the amount of ABM removed.

The above steps are repeated until all sites per panelist have beentested, i.e. the steps consisting of application of anti-stick agent orlotion comprising an anti-stick agent, application of ABM, applicationof weigh paper, application of weight, and removal of weigh paper. Forthe no-treatment control, application of agent or lotion is skipped andABM is applied directly to the skin site.

An example of a spreadsheet to collect the various weight measurementsand to calculate the percent (%) residual ABM left on the arm is asfollows:

Sub Site Trtmnt Syringe Syringe After ABM Applied ABM Removed % ABM Arm101 1 I 7.8561 7.6351 0.2210 0.1678 24.07 101 2 J 7.6343 7.4241 0.21020.1967 6.42 101 3 H 7.4223 7.2208 0.2015 0.1473 26.90 101 4 A 7.22007.0090 0.2110 0.1754 16.87 101 5 G 7.0080 6.8087 0.1993 0.1755 11.94 1016 B 7.8082 7.5957 0.2125 0.2042 3.91 101 7 F 7.5943 7.3862 0.2081 0.153626.19 101 8 C 6.9643 6.7592 0.2051 0.1526 25.60 101 9 E 7.3840 7.17250.2115 0.1984 6.19 101 10 D 7.1711 6.9678 0.2033 0.1788 12.05 Wherein:Sub refers to the subject number, which is minimally 101 to 108 andideally 101 to 110, i.e. the above chart would be replicated 8 to 10times to cover all panelists. Site refers to arm location, starting withthe left arm near the elbow (Site 1) and proceeding to the right armnear the wrist (Site 10). Trtmnt refers to the code of the treatmentapplied, typically a letter from A-J. Syringe refers to the initialweight of the syringe containing ABM. Syringe After refers to the finalweight of the syringe containing ABM once approximately 0.2 ml of ABMhas been dispensed onto a treatment site. ABM Applied is a calculatedvalue obtained from the equation Syringe − Syringe After = ABM Applied.ABM Removed refers to the weight of the ABM that has been captured onthe tared weight paper after the weigh paper has been peeled from atreatment site. % ABM Arm is a calculated value obtained from theequation ((ABM Applied − ABM Removed)/ABM Applied) × 100. This is ameasure of the percent (%) residual ABM on the skin surface aftertreatment.

The mean and standard error of the mean (“SEM”) for each treatment, e.g.A-J, for all panelists, e.g. 101-110, is calculated and graphed. FIG. 11is an illustration of an example of the percent of artificial bowelmovement residual left on a forearm following anti-stick treatment. InFIG. 11, the grey bar represents the mean of each treatment. The errorbar represents the SEM of each treatment. This example graph shows onlysix treatments for simplicity.

When the method is run correctly, the no treatment control may yield avalue between approximately 30% to 35% residual ABM.

This method may also be used to assess expressed lotion compositionsfrom commercially available wipe products. Expressed lotion compositionsare prepared by inserting the entire wipe stack of a non-expiredmarketed product into a pre-cleaned press capable of exerting about 80psi downward force on the stack. Ideally, the lower plate of the presscontains a channel into which the expressed lotion may collect, and ahole through which the expressed lotion may flow into a clean storagecontainer. An example of a suitable storage container is Catalog#83008-666 as available from VWR Scientific of West Chester, Pa. Allexpressed lotions are stored at room temperature prior to use.

On the day prior to the study, 10 ml of each anti-stick agent or lotioncomposition is transferred into a glass scintillation vial such asCatalog #66022-060 as available from VWR Scientific of West Chester, Pa.Each vial is labeled with the treatment code, e.g. A-J. On the day ofthe study, the anti-stick agent or lotion composition is drawn from thescintillation vial with the standard or positive displacement pipettorand applied to the respective treatment site as described in the method.By having the various treatments in the scintillation vials, it is veryeasy to rearrange the vials in between panelists to accommodate therandomization scheme for the study.

To ensure reproducible results, the Anti-Stick Screening Method shouldbe run at a room temperature of 21° C.±2° C. and at a relative humidityof 30-50%.

Preparation of Artificial Pasty Bowel Movement (ABM)

The following equipment is required:

-   -   an analytical balance accurate to ±0.001 g    -   a homogenizer capable of stirring the ingredients to        homogeneity, such as an Ika Labortechnik™ T25 basic or        equivalent as available from Ika-Werke GmbH and Co. KG of        Staufen, Germany.    -   a homogenizer probe to be used with the homogenizer, such as        Catalog #S25N 25F as available from Ika-Werke GmbH and Co. KG of        Staufen, Germany.

The following reagents are required:

-   -   Feclone™ Powder #4, available from SiliClone Studio, Valley        Forge, Pa., as Catalog Number Feclone BFPS-4.    -   Feclone™ Powder #6, available from SiliClone Studio, Valley        Forge, Pa., as Catalog Number BFPS-6.    -   Feclone™ Powder #7, available from SiliClone Studio, Valley        Forge, Pa., as Catalog Number BFPS-7.    -   Carbopol™ 981, available from BF Goodrich, Cleveland, Ohio.    -   Deionized water.

The following quantities of the above reagents are required:

Ingredient Grams Deionized water for Carbopol ™ solution 78.78 Feclone ™powder #4 6.600 Feclone ™ powder #6 6.600 Feclone ™ powder #7 6.600Carbopol ™ 981 0.900

The procedure to prepare the ABM consists of the following steps:

A. Preparation of Carbopol™ Solution

-   -   1. Weigh 78.78 g±0.01 g of deionized water in a 250 ml beaker.    -   2. Weigh 0.900 g±0.001 g of Carbopol™ on weigh paper.    -   3. Put beaker on a magnetic stirrer and set speed at 400 rpm.    -   4. Add Carbopol™ powder slowly to the water, over the span of        about 5 minutes. While adding the Carbopol™, increase the        stirring speed slowly to 600 rpm.    -   5. Once the Carbopol™ powder has been added to the water, cover        the beaker and continue mixing at 600 rpm for 15 minutes. The        Carbopol™ powder must be completely dispersed, i.e. a        transparent gel without any agglomerates.    -   6. Set up a hot plate at 150° C. Place the Carbopol™ solution on        the hot plate and continue mixing at 600 rpm until the solution        is heated to 81° C. to 83° C.        B. Preparation of ABM Mixture    -   1. Weigh 6.600 g±0.01 g each of Feclone powders #4, #6, and #7        into a beaker and mix well.    -   2. Using a T25 basic or equivalent homogenizer with a        homogenizer probe, stir the Carbopol™ solution at 8000 rpm for        about 30 seconds before proceeding with Step 3.    -   3. To the Carbopol™ solution that is being stirred, slowly add        the Feclone™ powder mixture, about one quarter of the total at a        time. Ensure that the Feclone™ powder mixture gets pulled        through the homogenizer probe during addition, i.e. is        thoroughly mixed into the pasty composition that is forming If        necessary, use a spatula to facilitate incorporation of the        Feclone™ powder mixture into the composition.    -   4. After all of the Feclone™ powder mixture has been added,        continue mixing with the homogenizer at 8000 rpm for an        additional 5 minutes, using the spatula to push the pasty        composition towards the homogenizer probe. The composition        should be thoroughly mixed and appear homogeneous.

The finished ABM may be placed in a container, such as Catalog#14233-954 as available from VWR Scientific of West Chester, Pa., andstored in the refrigerator for up to 30 days. After 30 days, a newsample should be prepared for further experiments. The container must betightly sealed to avoid drying out of the ABM.

Prior to using the ABM in the Anti-Stick Screening Method, the ABM mustbe removed from the refrigerator and allowed to adjust back to roomtemperature. An easy way to accomplish this is to fill a 10 ml syringe,such as Catalog #BD301604 as available from VWR Scientific of WestChester, Pa., with cold ABM and then allow the syringe to equilibrate toroom temperature on a counter top. Equilibration typically takes about15 minutes. The 10 ml syringe can then be used to fill the 1 ml syringedescribed in the Anti-Stick Screening Method.

EXAMPLES

The lotion compositions of Examples 1 through 32 are contacted asdescribed earlier with a substrate such as Fibrella 3160, a 58 grams/m²nonwoven comprising a blend of 40% viscose fibers and 60% polypropylenefibers as is available from Suominen of Tampere, Finland or any othersubstrate deemed suitable for use.

In the Examples, “Q.S” refers herein to “quantum sufficit” and is asufficient percentage of water added to the composition to bring theoverall composition to 100%.

Weight Percent Components Example 1 Example 2 Example 3 Example 4Example 5 Water Q.S. Q.S. Q.S. Q.S. Q.S. PEG400 Phos Ester DV7656* 4.000PEG600 Phos Ester DV7658* 4.000 PEG425 Phos Ester DV8094* 4.000PEG425/PEG400 Phos Ester DV8097* 4.000 Silicone Polyether DV7425*10.000  Weight Percent Components Example 6 Example 7 Example 8 Example9 Example 10 Water Q.S. Q.S. Q.S. Q.S. Q.S. Disodium EDTA 0.100 0.1000.100 0.100 0.100 Iodopropynylbutylcarbamate 0.009 0.009 0.009 0.0090.009 Benzyl Alcohol 0.500 0.500 0.500 0.500 0.500 Suttocide ® A 50%Solution 0.150 0.150 0.150 0.150 0.150 PEG400 Phos Ester DV7656* 4.000PEG600 Phos Ester DV7658* 3.000 PPG425 Phos Ester DV8094* 4.000PPG425/PEG400 Phos Ester DV8097* 3.000 Silicone Polyether DV7425* 9.000Weight Percent Components Example 11 Example 12 Example 13 Example 14Example 15 Water Q.S. Q.S. Q.S. Q.S. Q.S. Disodium EDTA 0.100 0.1000.100 0.100 0.100 PEG-40 Hydrog. Castor Oil 0.400 0.400 0.400 0.4000.400 Propylene Glycol 1.500 1.500 1.500 1.500 1.500 Phenoxyethanol0.800 0.800 0.800 0.800 0.800 Methyl Paraben 0.150 0.150 0.150 0.1500.150 Ethyl Paraben 0.050 0.050 0.050 0.050 0.050 Propyl Paraben 0.0500.050 0.050 0.050 0.050 PEG400 Phos Ester DV7656* 3.000 PEG600 PhosEster DV7658* 4.000 PPG425 Phos Ester DV8094* 3.000 PPG425/PEG400 PhosEster DV8097* 4.000 Silicone Polyether DV7425* 8.000 Weight PercentComponents Example 16 Example 17 Example 18 Example 19 Example 20 WaterQ.S. Q.S. Q.S. Q.S. Q.S. Disodium EDTA 0.100 0.100 0.100 0.100 0.100PEG-40 Hydrog. Castor Oil 0.400 0.400 0.400 0.400 0.400 Propylene Glycol1.500 1.500 1.500 1.500 1.500 Phenoxyethanol 0.800 0.800 0.800 0.8000.800 Methyl Paraben 0.150 0.150 0.150 0.150 0.150 Ethyl Paraben 0.0500.050 0.050 0.050 0.050 Propyl Paraben 0.050 0.050 0.050 0.050 0.050Xanthan Gum 0.180 0.180 0.180 0.180 0.180 Abil Care 85 0.100 0.100 0.1000.100 0.100 Trilaureth-4 Phosphate 0.400 0.400 0.400 0.400 0.400Monobasic Sodium Phosphate 0.180 0.180 0.180 0.180 0.180 Perfume 0.0700.070 0.070 0.070 0.070 PEG400 Phos Ester DV7656* 1.000 PEG600 PhosEster DV7658* 2.000 PEG425 Phos Ester DV8094* 1.000 PPG425/PEG400 PhosEster DV8097* 2.000 Silicone Polyether DV7425* 6.000 Weight PercentComponents Example 21 Example 22 Example 23 Example 24 Example 25 WaterQ.S. Q.S. Q.S. Q.S. Q.S. Disodium EDTA 0.100 0.100 0.100 0.100 0.100Iodopropynylbutylcarbamate 0.009 0.009 0.009 0.009 0.009 Benzyl Alcohol0.500 0.500 0.500 0.500 0.500 Suttocide ® A 50% Solution 0.150 0.1500.150 0.150 0.150 Xanthan Gum 0.180 0.180 0.180 0.180 0.180 PEG40Hydrog. Castor Oil 0.550 0.550 0.550 0.550 0.550 Abil Care 85 0.1000.100 0.100 0.100 0.100 Citric Acid 0.055 0.055 0.055 0.055 0.055Perfume 0.070 0.070 0.070 0.070 0.070 PEG400 Phos Ester DV7656* 2.000PEG600 Phos Ester DV7658* 1.000 PPG425 Phos Ester DV8094* 2.000PPG425/PEG400 Phos Ester DV8097* 1.000 Silicone Polyether DV7425* 6.000Weight Percent Components Example 26 Example 27 Example 28 Water Q.S.Q.S. Q.S. Disodium EDTA 0.100 0.100 Iodopropynylbutylcarbamate 0.0090.009 Benzyl Alcohol 0.500 0.500 Suttocide ® A 50% Solution 0.150 0.150Xanthan Gum 0.180 PEG40 Hydrog. Castor Oil 0.550 Abil Care 85 0.100Citric Acid 0.055 Perfume 0.070 Glycerin 50.000 Carbowax ® 400 25.000I-Phosphonate Ethoxylate DV7436* 8.000 Weight Percent Components Example29 Example 30 Example 31 Example 32 Water Q.S. Q.S. Q.S. Q.S. DisodiumEDTA 0.100 0.100 0.100 0.100 Xanthan Gum 0.180 0.180 0.180 0.180 AbilCare 85 0.100 0.100 0.100 0.100 Sodium Benzoate 0.120 0.120 0.120 0.120PEG40 Hydrog. Castor Oil 0.440 0.440 0.440 0.440 Citric Acid 0.530 0.5300.530 0.530 Trisodium Citrate 0.390 0.390 0.390 0.390 Benzyl Alcohol0.300 0.300 0.300 0.300 Perfume 0.070 0.070 0.070 0.070 Euxyl ®PE9010^(Δ) 0.300 0.300 0.300 0.300 PEG400 Phos Ester DV7656* 4.000Silicone Polyether DV7425* 7.000 1-Phosphonate Ethoxylate DV7436* 6.000Carbowax ® 400 30.000 *As supplied by Rhodia, Inc., 350 George PattersonBlvd., Bristol, PA 19007 ^(Δ)As available from Schuelke and Mayr GmbH ofNorderstedt, Germany.

The dimensions and values disclosed herein are not to be understood asbeing strictly limited to the exact numerical values recited. Instead,unless otherwise specified, each such dimension is intended to mean boththe recited value and a functionally equivalent range surrounding thatvalue. For example, a dimension disclosed as “40 mm” is intended to mean“about 40 mm”.

All documents cited in the Detailed Description of the Invention are, inrelevant part, incorporated herein by reference; the citation of anydocument is not to be construed as an admission that it is prior artwith respect to the present invention. To the extent that any meaning ordefinition of a term in this written document conflicts with any meaningor definition of the term in a document incorporated by reference, themeaning or definition assigned to the term in this written documentshall govern.

While particular embodiments of the present invention have beenillustrated and described, it would be obvious to those skilled in theart that various other changes and modifications can be made withoutdeparting from the spirit and scope of the invention. It is thereforeintended to cover in the appended claims all such changes andmodifications that are within the scope of this invention.

What is claimed is:
 1. A lotioned wipe product comprising: a. asubstrate; b. a lotion comprising an anti-stick agent selected from thegroup consisting of mono-functional heteroatom oxide ethoxylated ethersand combinations thereof, wherein said lotion is in contact with saidsubstrate; and wherein said lotion is effective at leaving less thanabout 10% residual soils or exudates as measured by the Anti-StickScreening Method.
 2. The wipe product of claim 1, wherein saidheteroatom oxide is selected from the group consisting of phosphonate,sulphonate, carbonate and combinations thereof.
 3. The wipe product ofclaim 1, wherein said mono-functional heteroatom oxide ethoxylated etheris a 1-phosphonate ethoxylate.
 4. The wipe product of claim 1 whereinsaid anti-stick agent is water soluble.
 5. The wipe product of claim 1wherein said lotion further comprises an emollient and a surfactant. 6.The wipe product of claim 1 wherein said substrate comprises hydrophobicfibers.
 7. The wipe product of claim 1 wherein said substrate istextured.
 8. An article of commerce comprising a container housing saidwipe product of claim
 1. 9. A method of preventing the adherence ofsoils or exudates to the skin comprising a step of contacting said skinwith said wipe product of claim
 1. 10. The wipe product of claim 1wherein said lotion comprises equal to or less than about 50% w/w ofsaid anti-stick agent.
 11. The wipe product of claim 1 wherein saidlotion comprises equal to or less than about 25% w/w of said anti-stickagent.
 12. The wipe product of claim 1 wherein said lotion comprisesfrom about 0.05% w/w to about 50% w/w of said anti-stick agent.